What is the Corning cellcube cell culture system?

The Corning CellCube cell culture system provides a compact, perfusion-based method for the mass culture of attachment-dependent cells.

Does Corning offer closed system cellcube modules?

Corning offers closed system CellCube modules available preassembled with AseptiQuik® connectors, as well as a selection of circulation loops that facilitate adherent cell culture scale-up and integrate seamlessly with AseptiQuik and MPC connectors. *Peristaltic pump, controller, and SUB sold separately.

How does the Corning cellcube system work?

The culture medium is perfused through the Corning CellCube system by a peristaltic pump. This allows media to flow in from the controlled single use bioreactor (SUB) into the CellCube module and back to the SUB for conditioning.

What are cellcube modules?

CellCube modules consist of a series of 10, 25, or 100 parallel, polystyrene plates joined to create thin, sealed laminar flow spaces between adjacent plates. CellCube modules are available with either a Tissue Culture (TC)-treated growth surface or Corning CellBIND® surface for cell attachment.

How does the cellcube system work?

Utilizing a perfusion-based design, the CellCube system is able to mimic the constant fluid flow of in vivo conditions and reliably distribute nutrients and oxygen with low differential gradients across all attached cells throughout the modules.

What surface treatments are available for cellcube modules?

CellCube modules are available with either a Tissue Culture (TC)-treated growth surface or Corning CellBIND® surface for cell attachment. The surface treatment is applied to both sides of each layer to achieve available surface area ranging from 8,500 cm2 to 85,000 cm2 in a compact footprint.