Hypoxia using fluorescent lamps and solar power generation

Turn-on Fluorescent Biosensors for Imaging Hypoxia

A novel "turn-on" fluorescent probe HP for hypoxia imaging was designed and synthesized based on rhodamine B and a naphthalimide fluorophore. The fluorescence of HP is very weak owing to the FRET effect

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Hypoxia Using pH-Regulated and Target-Activated Fluorescent

Hypoxia Using pH-Regulated and Target-Activated Fluorescent Nanoprobes Cong Zhu,a Zhen Zou,b Caixia Huang,a Jing Zheng,a,* Na Liu,a Jishan Li,a Ronghua Yangb aState Key

Simulation of hypoxia of myocardial cells in microfluidic systems

The effectiveness of biochemical simulation of hypoxia was studied using two fluorescent dyes: carbocyanine iodide (JC-1) and Fluo-4.

An unexpected strategy to alleviate hypoxia limitation of

A versatile fluorescent molecular probe endowed with singlet oxygen generation under white-light photosensitization. Dyes Pigments 142, 77–87 (2017). Article CAS Google

Achieving efficient photodynamic therapy under both normoxia

The cells were further incubated for an additional 1 h under 5% O 2 for the measurements under hypoxia. PDT treatment was performed using a white light (400–800 nm) obtained by a xenon

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In vivo imaging of hypoxia generation stimulated by testosterone using

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Genetically Encoded Reporters to Monitor Hypoxia

Fluorescence imaging using genetically encoded reporters enables hypoxia and oxygen imaging with cellular resolution. Thereby unrestricted visualization of hypoxic cells and regions

Genetically Encoded Reporters to Monitor Hypoxia

Erapaneedi R, Belousov VV, Schäfers M et al (2016) A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level. EMBO J: European

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Here, we describe a unique approach to permanently mark cells that experience hypoxia with a fluorescent protein switch that is maintained even after a cell is reoxygenated.

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Synthetic biology of hypoxia

Fusions between O 2-dependent and O 2-independent fluorescent proteins have been successfully used to spot hypoxia in human cells (Erapaneedi et al., 2016). The amenability of tFTs as in vivo sensors in plants

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In vivo imaging of hypoxia generation stimulated by

Hypoxia generation is caused by insufficient oxygen (O2) in aggressively proliferating cancer cells or tumors, which can lead to resistance to chemotherapy and radiotherapy. However, current hypoxic probes have been evaluated only

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The recent advances in photocatalysis have opened a variety of new possibilities for energy and biomedical applications. In particular, plasmonic photocatalysis

Whole-Body and Whole-Organ 3D Imaging of Hypoxia Using an

The whole-body and whole-organ imaging of hypoxia, an important microenvironment, at single-cell resolution at single-cell resolution using activatable covalent

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Modularized supramolecular assemblies for hypoxia-activatable

Furthermore, quantitative results (Figure 4E) showed that the fluorescence intensity at tumor sites in mice increased following laser irradiation by 1.36 folds, attributable to the light-modulated

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Genetically Encoded Reporters to Monitor Hypoxia

Hypoxia resulting from an imbalance of oxygen availability and consumption defines a metabolic cellular state with a profound impact on developmental processes, tissue

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Detection of Hypoxia in 2D and 3D Cell Culture Systems Using

We show that hypoxia reporter MSCs exhibit a hypoxia-induced fluorescence signal in both 2D and 3D cultivation platforms with fast decay kinetics after reoxygenation, rendering it a

(PDF) Whole-body and whole-organ 3D imaging of hypoxia using

The ability of designed activatable fluorescent probes for hypoxia detection. a Chemical structures of pimonidazole and the designed fluorescent probe for hypoxia, Pimo

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Monitoring cellular redox state under hypoxia using a fluorescent

More recently, a novel family of hypoxia sensors have been described, based on UnaG, a fluorescent protein from Japanese freshwater eel that does not rely on O2 to adopt

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Monitoring cellular redox state under hypoxia using a fluorescent

A highly fluorescent protein from the Japanese freshwater eel, UnaG, was recently identified [10].UnaG belongs to the fatty-acid-binding protein family, and its

Hypoxia using fluorescent lamps and solar power generation

6 FAQs about [Hypoxia using fluorescent lamps and solar power generation]

How does hypoxia affect fluorescence?

Under hypoxia conditions, the azo-bond is reduced and the fluorescence at 581 nm enhances dramatically as a result of disintegration of the quencher structure. Verified by the cyclic voltammetry redn. potential and proposed product HPN, the probe HP could undergo the chem. and cytochrome P 450 enzymic redn. quickly.

Can a covalent fluorescent probe be used for 3D imaging of hypoxia?

Please reconnect Whole-Body and Whole-Organ 3D Imaging of Hypoxia Using an Activatable Covalent Fluorescent Probe Compatible with Tissue Clearing Elucidation of biological phenomena requires imaging of microenvironments in vivo.

Can fluorescent probes detect hypoxic tumors?

The use of fluorescent probes is an evolving field for detecting hypoxic tumors in biol. systems. The present review is an attempt to provide a contextual knowledge on the prominent role of tumor hypoxia in cancer progression and dissemination.

Is bilirubin-inducible fluorescent protein a heterogeneity in tumor hypoxia?

A bilirubin-inducible fluorescent protein from eel muscle A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level Free radicals in the physiological control of cell function

What is a hypoxia-sensitive fluorescent probe?

New hypoxia-sensitive fluorescent probes were developed; they consist of a rhodamine moiety with an azo group directly conjugated to the fluorophore. Because of an ultrafast conformational change around the NN bond, the compds. are nonfluorescent under normoxia.

Is rounag a hypoxia sensor?

Such oxygen independence of roUnaG fluorescence was further highlighted by fusing a red fluorescent protein (mCherry) (Fig. 3F and G ), suggesting that the tandem could function as a fluorescent hypoxia sensor for the distinction of hypoxic and reoxygenated cells ( Fig. 3H).

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